PDB | 6roj Activated Drs2p-Cdc50p

Cryo-EM structure of the activated Drs2p-Cdc50p

label Keywords
lipid flippase, lipid transport, p-type atpase, ps transport.
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
MAGNESIUM ION, (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate

Original publication

import_contacts Title
Structure and autoregulation of a P4-ATPase lipid flippase.
import_contacts Journal
Nature 2019
import_contacts DOI
10.1038/s41586-019-1344-7
person Authors
Ash, M.R., Montigny, C., Karlsen, J.L., Lenoir, G., Moeller, A., Boesen, T., Januliene, D., Lyons, J.A., Ulstrup, J.J., Kuhlbrandt, W., Dieudonne, T., Timcenko, M., Nissen, P.

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