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      PDB | 6qee Nanodisc reconstituted Human-mouse chimeric ABCB1 (ABCB1HM)-EQ mutant

      Nanodisc reconstituted Human-mouse chimeric ABCB1 (ABCB1HM)-EQ mutant in complex with UIC2 Fab and Zosuquidar.

      label Keywords
      abcb1, p-glycoprotein, p-gp, multidrug transporter, abc transporter, zosuquidar, membrane transporter, membrane protein
      event_note Published
      11/13/2024
      filter_center_focus Method
      ELECTRON MICROSCOPY
      add_circle Ligands
      2-acetamido-2-deoxy-beta-D-glucopyranose, Zosuquidar, CHOLESTEROL, 1,2-Distearoyl-sn-glycerophosphoethanolamine

      Original publication

      import_contacts Title
      Structural insight into substrate and inhibitor discrimination by human P-glycoprotein.
      import_contacts Journal
      Science 2019
      import_contacts DOI
      10.1126/science.aav7102
      person Authors
      Locher, K.P., Kowal, J., Alam, A., Roninson, I., Broude, E.

      Read article from Science

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Locher, K.P., Kowal, J., Alam, A., Roninson, I., Broude, E. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

      play_circle_outline6qee_default_dppc

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