PDB | 6puu Human TRPM2 bound to 8-Br-cADPR and calcium
Human TRPM2 bound to 8-Br-cADPR and calcium
label Keywords
trpm2 channel, 8-br-cadpr, calcium, transport protein
event_note Published
03/20/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(2R,3R,4S,5R,13R,14S,15R,16R)-24-amino-18-bromo-3,4,14,15-tetrahydroxy-7,9,11,25,26-pentaoxa-17,19,22-triaza-1-azonia-8 ,10-diphosphapentacyclo[18.3.1.1^2,5^.1^13,16^.0^17,21^]hexacosa-1(24),18,20,22-tetraene-8,10-diolate 8,10-dioxide, CALCIUM ION
Original publication
import_contacts Title
Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel.
import_contacts Journal
Elife 2019
import_contacts DOI
10.7554/eLife.50175
person Authors
Lu, W., Huang, Y., Roth, B., Du, J.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Lu, W., Huang, Y., Roth, B., Du, J. , provided free of copyright via the Protein DataBank. View original data or read license terms.
