PDB | 6ps3 XFEL beta2 AR structure by ligand exchange
XFEL beta2 AR structure by ligand exchange from Timolol to Carvedilol.
label Keywords
gpcr, complex-lcp method, sbdd, drug design, xfel, lcp-sfx, ligand exchange, timolol, cavedilol, b2ar, beta2ar, membrane protein
event_note Published
10/16/2024
blur_on Resolution
2.5 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(2S)-1-(8H-CARBAZOL-4-YLOXY)-3-[2-(2-METHOXYPHENOXY)ETHYLAMINO]PROPAN-2-OL, SULFATE ION, CHOLESTEROL, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, OLEIC ACID
Original publication
import_contacts Title
Toward G protein-coupled receptor structure-based drug design using X-ray lasers.
import_contacts Journal
Iucrj 2019
import_contacts DOI
10.1107/S2052252519013137
person Authors
Nakane, T., Moraes, I., Stauch, B., Joti, Y., Zatsepin, N., Li, C., Weierstall, U., Iwata, S., Han, G.W., Tono, K., Nango, E., Ishchenko, A., Cherezov, V., Tanaka, R., Gati, C., Shiriaeva, A., Batyuk, A., Liu, W.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Nakane, T., Moraes, I., Stauch, B., Joti, Y., Zatsepin, N., Li, C., Weierstall, U., Iwata, S., Han, G.W., Tono, K., Nango, E., Ishchenko, A., Cherezov, V., Tanaka, R., Gati, C., Shiriaeva, A., Batyuk, A., Liu, W. , provided free of copyright via the Protein DataBank. View original data or read license terms.
