PDB | 6pqq Human TRPA1 C621S mutant in the apo state

Cryo-EM structure of human TRPA1 C621S mutant in the apo state

label Keywords
ion channel, trp channel, trpa channel, trpa1 channel, irritant sensing, apo state, membrane protein, transport protein
event_note Published
03/20/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate

Original publication

import_contacts Title
Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.
import_contacts Journal
Neuron 2020
import_contacts DOI
10.1016/j.neuron.2019.11.023
person Authors
Borgnia, M.J., Zubcevic, L., Lee, S.Y., Suo, Y., He, Q., Wang, Z., Ji, R.R., Hsu, A.L.

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