PDB | 6oyh MraY bound to carbacaprazamycin

Crystal structure of MraY bound to carbacaprazamycin

label Keywords
peptidoglycan biosynthesis, antibiotic target, integral membrane enzyme, translocase, membrane protein, membrane protein-transferase complex
event_note Published
11/20/2024
blur_on Resolution
2.95 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(5S)-5'-O-(5-amino-5-deoxy-beta-D-ribofuranosyl)-5'-C-[(2S,5S,6S)-5-carboxy-6-heptadecyl-1,4-dimethyl-3-oxo-1,4-diazepan-2-yl]uridine

Original publication

import_contacts Title
Chemical logic of MraY inhibition by antibacterial nucleoside natural products.
import_contacts Journal
Nat Commun 2019
import_contacts DOI
10.1038/s41467-019-10957-9
person Authors
Lee, K., Hong, J., Kaeser, B., Terasawa, Y., Mashalidis, E.H., Lee, S.Y., Ichikawa, S., Katsuyama, A., Kwon, D.Y.

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