PDB | 6ot0 Structure of human Smoothened-Gi complex
Structure of human Smoothened-Gi complex
label Keywords
gpcr, complex, hedgehog signaling, signaling protein
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
17-[3-(3,3-DIMETHYL-OXIRANYL)-1-METHYL-PROPYL]-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYC LOPENTA[A]PHENANTHREN-3-OL
Original publication
import_contacts Title
Cryo-EM structure of oxysterol-bound human Smoothened coupled to a heterotrimeric Gi.
import_contacts Journal
Nature 2019
import_contacts DOI
10.1038/s41586-019-1286-0
person Authors
Zhang, C., Liu, H., McDonald, J., Qi, X., Thompson, B., Li, X.
copyrightData provided by Research Collaboration for Structural Biology, Zhang, C., Liu, H., McDonald, J., Qi, X., Thompson, B., Li, X. , provided free of copyright via the Protein DataBank. View original data or read license terms.