PDB | 6os2 Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to TRV026
Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to TRV026
label Keywords
gpcr, membrane protein
event_note Published
11/06/2024
blur_on Resolution
2.7 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL
Original publication
import_contacts Title
Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
import_contacts Journal
Science 2020
import_contacts DOI
10.1126/science.aay9813
person Authors
Staus, D.P., Lefkowitz, R.J., McMahon, C., Dror, R.O., Kruse, A.C., Latorraca, N.R., Skiba, M.A., Wingler, L.M., Kleinhenz, A.L.W., Suomivuori, C.M.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Staus, D.P., Lefkowitz, R.J., McMahon, C., Dror, R.O., Kruse, A.C., Latorraca, N.R., Skiba, M.A., Wingler, L.M., Kleinhenz, A.L.W., Suomivuori, C.M. , provided free of copyright via the Protein DataBank. View original data or read license terms.
