PDB | 6os0 Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to angiotensin II

Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to angiotensin II

label Keywords
gpcr, nanobody, membrane protein
event_note Published
11/20/2024
blur_on Resolution
2.9 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION

Original publication

import_contacts Title
Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
import_contacts Journal
Science 2020
import_contacts DOI
10.1126/science.aay9813
person Authors
Staus, D.P., Lefkowitz, R.J., McMahon, C., Dror, R.O., Kruse, A.C., Latorraca, N.R., Skiba, M.A., Wingler, L.M., Kleinhenz, A.L.W., Suomivuori, C.M.

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