PDB | 6ol9 Structure of the M5 muscarinic acetylcholine receptor (M5-T4L) bound to tiotropium
Structure of the M5 muscarinic acetylcholine receptor (M5-T4L) bound to tiotropium
label Keywords
gpcr inhibitor complex, membrane protein, hydrolase-hydrolase inhibitor complex
event_note Published
11/20/2024
blur_on Resolution
2.541 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
OLEIC ACID, (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
Original publication
import_contacts Title
Crystal structure of the M5muscarinic acetylcholine receptor.
import_contacts Journal
Proc.Natl.Acad.Sci.USA 2019
import_contacts DOI
10.1073/pnas.1914446116
person Authors
Sexton, P.M., Langmead, C.J., Tobin, A.B., Hirata, K., Gentry, P.R., van der Westhuizen, E.T., Vuckovic, Z., Rahmani, R., Burger, W.A.C., Valant, C., Thompson, G., Berizzi, A.E., Varghese, S., Thal, D.M., Baell, J.B., Christopoulos, A., Lindsley, C.W.
copyrightData provided by Research Collaboration for Structural Biology, Sexton, P.M., Langmead, C.J., Tobin, A.B., Hirata, K., Gentry, P.R., van der Westhuizen, E.T., Vuckovic, Z., Rahmani, R., Burger, W.A.C., Valant, C., Thompson, G., Berizzi, A.E., Varghese, S., Thal, D.M., Baell, J.B., Christopoulos, A., Lindsley, C.W. , provided free of copyright via the Protein DataBank. View original data or read license terms.
