PDB | 6o1v Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and GLPG1837
Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and GLPG1837
label Keywords
abc transporter, anion channel, cystic fibrosis, membrane protein, glpg1837, hydrolase
event_note Published
03/20/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
N-(3-carbamoyl-5,5,7,7-tetramethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-2-yl)-1H-pyrazole-3-carboxamide, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL
Original publication
import_contacts Title
Structural identification of a hotspot on CFTR for potentiation.
import_contacts Journal
Science 2019
import_contacts DOI
10.1126/science.aaw7611
person Authors
Shoichet, B.K., Zhang, Z., Touhara, K.K., Liu, F., Chen, J., Levring, J., Levit, A.
copyrightData provided by Research Collaboration for Structural Biology, Shoichet, B.K., Zhang, Z., Touhara, K.K., Liu, F., Chen, J., Levring, J., Levit, A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
