PDB | 6ni3 B2V2R-Gs protein subcomplex of a GPCR-G protein-beta-arrestin mega-complex

B2V2R-Gs protein subcomplex of a GPCR-G protein-beta-arrestin mega-complex

label Keywords
gpcr, gs protein, signaling transducer, signaling protein-immune system complex
event_note Published
10/16/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one

Original publication

import_contacts Title
Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex.
import_contacts Journal
Nat.Struct.Mol.Biol. 2019
import_contacts DOI
10.1038/s41594-019-0330-y
person Authors
Lefkowitz, R.J., Triest, S., Nguyen, A.H., Marcink, T., Cahill 3rd, T.J., Sunahara, R., Mahoney, J.P., Thomsen, A.R.B., Tan, Y.Z., Steyaert, J., Hong, C., Molina, H., Chen, X., Dandey, V.P., Ben-Hail, D., Clarke, O.B., Yu, Z., Heissel, S., Samaan, F., Huang, R., Huang, L.Y., Little 4th, J., des Georges, A., Masoudi, A.

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