PDB | 6n4r Nav1.7 VSD2 (deactived state)
CryoEM structure of Nav1.7 VSD2 (deactived state) in complex with the gating modifier toxin ProTx2
label Keywords
voltage-gated sodium channel, gating modifier toxin, membrane protein
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
Original publication
import_contacts Title
Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin.
import_contacts Journal
Cell 2019
import_contacts DOI
10.1016/j.cell.2018.12.018
person Authors
Chen, J., Ciferri, C., Hackos, D.H., Kugel, C., Rohou, A., Li, T., Payandeh, J., Tzakoniati, F., Koth, C.M., Estevez, A., Xu, H., Wong, E., Arthur, C.P., Franke, Y.
copyrightData provided by Research Collaboration for Structural Biology, Chen, J., Ciferri, C., Hackos, D.H., Kugel, C., Rohou, A., Li, T., Payandeh, J., Tzakoniati, F., Koth, C.M., Estevez, A., Xu, H., Wong, E., Arthur, C.P., Franke, Y. , provided free of copyright via the Protein DataBank. View original data or read license terms.
