PDB | 6me2 Human melatonin receptor MT1
XFEL crystal structure of human melatonin receptor MT1 in complex with ramelteon
label Keywords
gpcr, melatonin receptor type 1a (mt1), membrane protein, ramelteon, xfel, lcp, pgs, circadian rhythm, jetlag
event_note Published
09/05/2018
blur_on Resolution
2.8 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
N-{2-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl}propanamide, OLEIC ACID, DI(HYDROXYETHYL)ETHER
Original publication
import_contacts Title
Structural basis of ligand recognition at the human MT1melatonin receptor.
import_contacts Journal
Nature 2019
import_contacts DOI
10.1038/s41586-019-1141-3
person Authors
Patel, N., Han, G.W., Ishchenko, A., Roth, B.L., Grandner, J.M., Michaelian, N., Yous, S., Stauch, B., Johansson, L.C., Zhu, L., Katritch, V., McCorvy, J.D., Grant, T.D., Liu, W., Brehm, W., Madsen, C., Weierstall, U., Cherezov, V., Slocum, S.T., Huang, X.P., Tribo, A.R., White, T.A., Batyuk, A., Olsen, R.H.J., Gati, C., Shiriaeva, A., Stevens, R.C.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Patel, N., Han, G.W., Ishchenko, A., Roth, B.L., Grandner, J.M., Michaelian, N., Yous, S., Stauch, B., Johansson, L.C., Zhu, L., Katritch, V., McCorvy, J.D., Grant, T.D., Liu, W., Brehm, W., Madsen, C., Weierstall, U., Cherezov, V., Slocum, S.T., Huang, X.P., Tribo, A.R., White, T.A., Batyuk, A., Olsen, R.H.J., Gati, C., Shiriaeva, A., Stevens, R.C. , provided free of copyright via the Protein DataBank. View original data or read license terms.
