PDB | 6lz0 Cryo-EM structure of human MCT1 in complex with Basigin-2 in the presence of lactate

Cryo-EM structure of human MCT1 in complex with Basigin-2 in the presence of lactate

label Keywords
lactate transporter, mct1, basigin-2, proton-coupled monocarboxylate transporter, transport protein
event_note Published
03/27/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(2S)-2-HYDROXYPROPANOIC ACID

Original publication

import_contacts Title
Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates.
import_contacts Journal
Cell 2021
import_contacts DOI
10.1016/j.cell.2020.11.043
person Authors
Yuan, Y., Zhu, A., Lei, J., Yan, C., Xu, H., Jiang, X., Zhang, S., Wang, N.

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