PDB | 6li0 Crystal structure of GPR52 in complex with agonist c17
Crystal structure of GPR52 in complex with agonist c17
label Keywords
human gpr52 receptor, class a, orphan gpcr, membrane protein, agonist c17, flavodoxin, lcp
event_note Published
10/23/2024
blur_on Resolution
2.2 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
N-(2-hydroxyethyl)-5-(hydroxymethyl)-3-methyl-1-[2-[[3-(trifluoromethyl)phenyl]methyl]-1-benzothiophen-7-yl]pyrazole-4-carboxamide, FLAVIN MONONUCLEOTIDE, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, CITRATE ANION
Original publication
import_contacts Title
Structural basis of ligand recognition and self-activation of orphan GPR52.
import_contacts Journal
Nature 2020
import_contacts DOI
10.1038/s41586-020-2019-0
person Authors
Zhao, S., Li, M., Xie, X., Lei, M., Chen, Y., Guo, S., Han, G.W., Wu, J., Wu, Y., Lin, X., Luo, Z., Yue, Y., Li, S., Wang, N., Xu, F., Wei, X.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Zhao, S., Li, M., Xie, X., Lei, M., Chen, Y., Guo, S., Han, G.W., Wu, J., Wu, Y., Lin, X., Luo, Z., Yue, Y., Li, S., Wang, N., Xu, F., Wei, X. , provided free of copyright via the Protein DataBank. View original data or read license terms.
