PDB | 6i53 Human synaptic alpha1-beta3-gamma2 GABAA receptor
Cryo-EM structure of the human synaptic alpha1-beta3-gamma2 GABAA receptor in complex with Megabody38 in a lipid nanodisc
label Keywords
ligand gated ion channel cys-loop receptor gaba-a receptor, transport protein
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Original publication
import_contacts Title
Cryo-EM structure of the human alpha 1 beta 3 gamma 2 GABAAreceptor in a lipid bilayer.
import_contacts Journal
Nature 2019
import_contacts DOI
10.1038/s41586-018-0833-4
person Authors
Uchanski, T., Masiulis, S., Malinauskas, T., Miller, K.W., Laverty, D., Zivanov, J., Steyaert, J., Aricescu, A.R., Stec, W.J., Pardon, E., Desai, R.
copyrightData provided by Research Collaboration for Structural Biology, Uchanski, T., Masiulis, S., Malinauskas, T., Miller, K.W., Laverty, D., Zivanov, J., Steyaert, J., Aricescu, A.R., Stec, W.J., Pardon, E., Desai, R. , provided free of copyright via the Protein DataBank. View original data or read license terms.
