PDB | 6hzm ABCG2 E211Q mutant bound to ATP and Magnesium (alternative placement of Magnesium
Cryo-EM structure of the ABCG2 E211Q mutant bound to ATP and Magnesium (alternative placement of Magnesium into the cryo-EM density)
label Keywords
multidrug transporter, membrane protein, cancer
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Original publication
import_contacts Title
Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states.
import_contacts Journal
Nature 2018
import_contacts DOI
10.1038/s41586-018-0680-3
person Authors
Locher, K.P., Jackson, S.M., Manolaridis, I., Kowal, J., Stahlberg, H., Taylor, N.M.I.
copyrightData provided by Research Collaboration for Structural Biology, Locher, K.P., Jackson, S.M., Manolaridis, I., Kowal, J., Stahlberg, H., Taylor, N.M.I. , provided free of copyright via the Protein DataBank. View original data or read license terms.