PDB | 6hk0 Pentameric ligand gated ion channel

X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) F16'S pore mutant (F247S) with alternate M4 conformation.

label Keywords
ion channel, pentameric ligand-gated ion channel, cya-loop receptor, membrane protein
event_note Published
01/17/2024
blur_on Resolution
3.45 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
DODECYL-BETA-D-MALTOSIDE

Original publication

import_contacts Title
A lipid site shapes the agonist response of a pentameric ligand-gated ion channel.
import_contacts Journal
Nat.Chem.Biol. 2019
import_contacts DOI
10.1038/s41589-019-0369-4
person Authors
Baenziger, J.E., Lynch, J., Brannigan, G., Evans, G.L., Bertrand, D., Nury, H., Henault, C.M., Spurny, R., Steyaert, J., Govaerts, C., Ulens, C., Woods, K., Estrada-Mondragon, A., Elberson, B.W., Cuello, L.G., Brams, M., Pardon, E.

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