PDB | 6hco ABCG2 E211Q mutant bound to estrone 3-sulfate and 5D3-Fab

Cryo-EM structure of the ABCG2 E211Q mutant bound to estrone 3-sulfate and 5D3-Fab

label Keywords
multidrug transporter, membrane protein, cancer
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
estrone 3-sulfate

Original publication

import_contacts Title
Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states.
import_contacts Journal
Nature 2018
import_contacts DOI
10.1038/s41586-018-0680-3
person Authors
Locher, K.P., Jackson, S.M., Manolaridis, I., Kowal, J., Stahlberg, H., Taylor, N.M.I.

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