PDB | 6gs4 Peptide transporter DtpA-nanobody

Crystal structure of peptide transporter DtpA-nanobody in complex with valganciclovir

label Keywords
peptide transporter, membrane protein, complex with nanobody, slc15 family member
event_note Published
11/06/2024
blur_on Resolution
2.645 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
[(2~{S})-2-[(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)methoxy]-3-oxidanyl-propyl] (2~{S})-2-azanyl-3-methyl-butanoate, DODECYL-BETA-D-MALTOSIDE

Original publication

import_contacts Title
Structure of Prototypic Peptide Transporter DtpA from E. coli in Complex with Valganciclovir Provides Insights into Drug Binding of Human PepT1.
import_contacts Journal
J. Am. Chem. Soc. 2019
import_contacts DOI
10.1021/jacs.8b11343
person Authors
Quistgaard, E.M., Bartels, K., Strauss, J., Kosinski, J., Flayhan, A., Ural-Blimke, Y., Steyaert, J., Pardon, E., Nielsen, R., Low, C., Rantos, V.

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