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      PDB | 6fli The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - Co-crystallization

      The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - Co-crystallization with 4-bromo cinnamic acid

      label Keywords
      pentameric ligand-gated ion channel., membrane protein
      event_note Published
      05/08/2024
      blur_on Resolution
      3 Å
      filter_center_focus Method
      X-RAY DIFFRACTION
      add_circle Ligands
      nonyl beta-D-glucopyranoside, 3-(4-bromophenyl)propanoic acid

      Original publication

      import_contacts Title
      Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation.
      import_contacts Journal
      Proc. Natl. Acad. Sci. U.S.A. 2018
      import_contacts DOI
      10.1073/pnas.1717700115
      person Authors
      Fourati, Z., Hu, H., Corringer, P.J., Sauguet, L., Nemecz, A., Delarue, M., Van Renterghem, C.

      Read article from Proc. Natl. Acad. Sci. U.S.A.

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Fourati, Z., Hu, H., Corringer, P.J., Sauguet, L., Nemecz, A., Delarue, M., Van Renterghem, C. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

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