PDB | 6fka N2C/D282C stabilized opsin bound to RS11

Crystal structure of N2C/D282C stabilized opsin bound to RS11

label Keywords
rhodopsin, g protein-coupled receptors, retinitis pigmentosa, signaling protein, sensory transduction, photoreceptor protein, kintegral membrane protein, vision, membrane, receptor, transducer photoreceptor, small molecule complex, membrane protein
event_note Published
10/16/2024
blur_on Resolution
2.7 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
PALMITIC ACID, octyl beta-D-glucopyranoside, (2~{S})-2-(3,4-dichlorophenyl)-3-methyl-1-spiro[1,3-benzodioxole-2,4'-piperidine]-1'-yl-butan-1-one

Original publication

import_contacts Title
Ligand channel in pharmacologically stabilized rhodopsin.
import_contacts Journal
Proc. Natl. Acad. Sci. U.S.A. 2018
import_contacts DOI
10.1073/pnas.1718084115
person Authors
Dawson, R.J.P., Bedoucha, M., Schmid, G., Rudolph, M.G., Grozinger, N., Mattle, D., Standfuss, J., Schertler, G.F.X., Hennig, M., Alker, A., Kekilli, D., Aebi, J., Kuhn, B.

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