PDB | 6dzy Ts2-active human serotonin transporter
Cryo-EM structure of the ts2-active human serotonin transporter in complex with 15B8 Fab and 8B6 ScFv bound to ibogaine
label Keywords
ibogaine, human serotonin transporter, fab, transport protein-immune system complex
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(5beta)-12-methoxyibogamine, DODECYL-BETA-D-MALTOSIDE
Original publication
import_contacts Title
Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
import_contacts Journal
Nature 2019
import_contacts DOI
10.1038/s41586-019-1135-1
person Authors
Wen, P.C., Coleman, J.A., Zhao, Z., Tajkhorshid, E., Gouaux, E., Yang, D., Yoshioka, C.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Wen, P.C., Coleman, J.A., Zhao, Z., Tajkhorshid, E., Gouaux, E., Yang, D., Yoshioka, C. , provided free of copyright via the Protein DataBank. View original data or read license terms.
