PDB | 6ds0 Structural Determinants of Activation and Biased Agonism at the 5-HT2B Receptor

Structural Determinants of Activation and Biased Agonism at the 5-HT2B Receptor

label Keywords
gpcr, 5ht2b, setotonin receptor, lisuride, membrane protein
event_note Published
10/30/2024
blur_on Resolution
3.188 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
CHOLESTEROL, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, (1S)-1-[(2-chloro-3,4-dimethoxyphenyl)methyl]-6-methyl-2,3,4,9-tetrahydro-1H-beta-carboline

Original publication

import_contacts Title
Structural determinants of 5-HT2Breceptor activation and biased agonism.
import_contacts Journal
Nat. Struct. Mol. Biol. 2018
import_contacts DOI
10.1038/s41594-018-0116-7
person Authors
Che, T., Liu, J., Jin, J., Olsen, R.H.J., Lansu, K., McCorvy, J.D., Wang, S., Wacker, D., Tribo, A.R., Roth, B.L., Agegnehu, B.

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