PDB | 6drz Structural Determinants of Activation and Biased Agonism at the 5-HT2B Receptor

Structural Determinants of Activation and Biased Agonism at the 5-HT2B Receptor

label Keywords
gpcr, 5ht2b, setotonin receptor, methysergide, membrane protein
event_note Published
11/20/2024
blur_on Resolution
3.102 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
CHOLESTEROL, OLEIC ACID, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, (8alpha)-N-[(2S)-1-hydroxybutan-2-yl]-1,6-dimethyl-9,10-didehydroergoline-8-carboxamide

Original publication

import_contacts Title
Structural determinants of 5-HT2Breceptor activation and biased agonism.
import_contacts Journal
Nat. Struct. Mol. Biol. 2018
import_contacts DOI
10.1038/s41594-018-0116-7
person Authors
Che, T., Liu, J., Jin, J., Olsen, R.H.J., Lansu, K., McCorvy, J.D., Wang, S., Wacker, D., Tribo, A.R., Roth, B.L., Agegnehu, B.

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