PDB | 6d35 Xenopus Smoothened

Crystal structure of Xenopus Smoothened in complex with cholesterol

label Keywords
gpcr, hedgehog signaling, class frizzled, sterol, membrane protein
event_note Published
11/20/2024
blur_on Resolution
3.9 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
CHOLESTEROL

Original publication

import_contacts Title
Structural Basis of Smoothened Activation in Hedgehog Signaling.
import_contacts Journal
Cell 2018
import_contacts DOI
10.1016/j.cell.2018.04.029
person Authors
Huang, P., Aravena, L., Wierbowski, B.M., Liu, J., Nedelcu, D., Kruse, A.C., Zheng, S., Salic, A., Kim, Y.

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