PDB | 6c9a Mouse TPC1 channel in the PtdIns(3,5)P2-bound state
Cryo-EM structure of mouse TPC1 channel in the PtdIns(3,5)P2-bound state
label Keywords
ion channel, membrane protein
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose
Original publication
import_contacts Title
Structural insights into the voltage and phospholipid activation of the mammalian TPC1 channel.
import_contacts Journal
Nature 2018
import_contacts DOI
10.1038/nature26139
person Authors
Guo, J., Chen, Q., She, J., Zeng, W., Bai, X.C., Jiang, Y.
copyrightData provided by Research Collaboration for Structural Biology, Guo, J., Chen, Q., She, J., Zeng, W., Bai, X.C., Jiang, Y. , provided free of copyright via the Protein DataBank. View original data or read license terms.
