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      PDB | 6c1r Human C5a receptor

      Crystal structure of human C5a receptor in complex with an orthosteric antagonist PMX53 and an allosteric antagonist avacopan

      label Keywords
      gpcr, membrane protein-inhibitor complex
      event_note Published
      01/05/2018
      blur_on Resolution
      2.2 Å
      filter_center_focus Method
      X-RAY DIFFRACTION
      add_circle Ligands
      avacopan, MALONATE ION, SODIUM ION, TRIETHYLENE GLYCOL, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, OLEIC ACID

      Original publication

      import_contacts Title
      Orthosteric and allosteric action of the C5a receptor antagonists.
      import_contacts Journal
      Nat. Struct. Mol. Biol. 2018
      import_contacts DOI
      10.1038/s41594-018-0067-z
      person Authors
      Deepak, R.N.V.K., Fan, H., Wang, L., Zhang, C., Chung, K.Y., Liu, H., Kim, H.R., Wei, Z.

      Read article from Nat. Struct. Mol. Biol.

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Deepak, R.N.V.K., Fan, H., Wang, L., Zhang, C., Chung, K.Y., Liu, H., Kim, H.R., Wei, Z. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

      play_circle_outline6c1r_default_dppc

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