PDB | 6c1q Human C5a receptor

Crystal structure of human C5a receptor in complex with an orthosteric antagonist PMX53 and an allosteric antagonist NDT9513727

label Keywords
gpcr, membrane protein
event_note Published
01/05/2018
blur_on Resolution
2.9 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
1-(1,3-benzodioxol-5-yl)-~{N}-(1,3-benzodioxol-5-ylmethyl)-~{N}-[(3-butyl-2,5-diphenyl-imidazol-4-yl)methyl]methanamine

Original publication

import_contacts Title
Orthosteric and allosteric action of the C5a receptor antagonists.
import_contacts Journal
Nat. Struct. Mol. Biol. 2018
import_contacts DOI
10.1038/s41594-018-0067-z
person Authors
Deepak, R.N.V.K., Fan, H., Wang, L., Zhang, C., Chung, K.Y., Liu, H., Kim, H.R., Wei, Z.

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