PDB | 6c1q Human C5a receptor
Crystal structure of human C5a receptor in complex with an orthosteric antagonist PMX53 and an allosteric antagonist NDT9513727
label Keywords
gpcr, membrane protein
event_note Published
01/05/2018
blur_on Resolution
2.9 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
1-(1,3-benzodioxol-5-yl)-~{N}-(1,3-benzodioxol-5-ylmethyl)-~{N}-[(3-butyl-2,5-diphenyl-imidazol-4-yl)methyl]methanamine
Original publication
import_contacts Title
Orthosteric and allosteric action of the C5a receptor antagonists.
import_contacts Journal
Nat. Struct. Mol. Biol. 2018
import_contacts DOI
10.1038/s41594-018-0067-z
person Authors
Deepak, R.N.V.K., Fan, H., Wang, L., Zhang, C., Chung, K.Y., Liu, H., Kim, H.R., Wei, Z.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Deepak, R.N.V.K., Fan, H., Wang, L., Zhang, C., Chung, K.Y., Liu, H., Kim, H.R., Wei, Z. , provided free of copyright via the Protein DataBank. View original data or read license terms.