PDB | 6bpp E. coli MsbA in complex with LPS and inhibitor G092

E. coli MsbA in complex with LPS and inhibitor G092

label Keywords
abc transporter, inhibitor, lps, msba, lipid transport
event_note Published
03/13/2024
blur_on Resolution
2.92 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(2E)-3-{6-[(1S)-1-(3-amino-2,6-dichlorophenyl)ethoxy]-4-cyclopropylquinolin-3-yl}prop-2-enoic acid, 3-HYDROXY-TETRADECANOIC ACID, LAURIC ACID, 1,2-Distearoyl-sn-glycerophosphoethanolamine, PHOSPHATE ION, MYRISTIC ACID

Original publication

import_contacts Title
Structural basis for dual-mode inhibition of the ABC transporter MsbA.
import_contacts Journal
Nature 2018
import_contacts DOI
10.1038/s41586-018-0083-5
person Authors
Kiefer, J.R., Labadie, S.S., Quinn, J., Koehler, M.F.T., Garcia, N.K., Wecksler, A.T., Franke, Y., Miu, A., Reichelt, M., Payandeh, J., Hu, H., Zilberleyb, I., Maurer, T., Nishiyama, M., Clark, K., Xu, Y., Tam, C., Ho, H., Alexander, M.K., Lu, Y., Austin, C.D., Purkey, H.E., Wang, J., Liang, J., Sellers, B.D., Oh, A., Wang, L., Beresini, M.H., Verma, V., Koth, C.M., Tan, M.W., Shriver, S.

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