PDB | 6boc Influenza A M2 transmembrane domain bound to rimantadine in the Inward(open) conformation
Influenza A M2 transmembrane domain bound to rimantadine in the Inward(open) conformation
label Keywords
influenza m2, proton channel, membrane protein, rimantadine
event_note Published
11/20/2024
blur_on Resolution
2.25 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
CHLORIDE ION, (1S)-1-[(3R,5R,7R)-tricyclo[3.3.1.1~3,7~]decan-1-yl]ethan-1-amine, RIMANTADINE, SODIUM ION
Original publication
import_contacts Title
Inhibitors of the M2 Proton Channel Engage and Disrupt Transmembrane Networks of Hydrogen-Bonded Waters.
import_contacts Journal
J. Am. Chem. Soc. 2018
import_contacts DOI
10.1021/jacs.8b06741
person Authors
Wang, J., Polizzi, N.F., Kolocouris, A., DeGrado, W.F., Thomaston, J.L., Konstantinidi, A.
copyrightData provided by Research Collaboration for Structural Biology, Wang, J., Polizzi, N.F., Kolocouris, A., DeGrado, W.F., Thomaston, J.L., Konstantinidi, A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
