PDB | 6bmz Influenza A M2 transmembrane domain bound to a spiroadamantane inhibitor
Influenza A M2 transmembrane domain bound to a spiroadamantane inhibitor
label Keywords
influenza m2, proton channel, membrane protein, spiroadamantane
event_note Published
10/30/2024
blur_on Resolution
2.634 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(1r,1'S,3'S,5'S,7'S)-spiro[cyclohexane-1,2'-tricyclo[3.3.1.1~3,7~]decan]-4-amine, CHLORIDE ION
Original publication
import_contacts Title
Inhibitors of the M2 Proton Channel Engage and Disrupt Transmembrane Networks of Hydrogen-Bonded Waters.
import_contacts Journal
J. Am. Chem. Soc. 2018
import_contacts DOI
10.1021/jacs.8b06741
person Authors
Wang, J., Polizzi, N.F., Kolocouris, A., DeGrado, W.F., Thomaston, J.L., Konstantinidi, A.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Wang, J., Polizzi, N.F., Kolocouris, A., DeGrado, W.F., Thomaston, J.L., Konstantinidi, A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
