PDB | 6b73 Nanobody-stabilized active state of the kappa-opioid receptor
Crystal Structure of a nanobody-stabilized active state of the kappa-opioid receptor
label Keywords
gpcr, opioid receptor, addiction, active state, nanobody, structure-function, morphinan, lcp, membrane protein, membrane protein-agonist complex
event_note Published
10/30/2024
blur_on Resolution
3.1 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
N-[(5alpha,6beta)-17-(cyclopropylmethyl)-3-hydroxy-7,8-didehydro-4,5-epoxymorphinan-6-yl]-3-iodobenzamide, CHOLESTEROL, OLEIC ACID
Original publication
import_contacts Title
Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.
import_contacts Journal
Cell 2018
import_contacts DOI
10.1016/j.cell.2017.12.011
person Authors
Han, G.W., Roth, B.L., Krumm, B.E., Katritch, V., Steyaert, J., Pasternak, G.W., McCorvy, J.D., Wang, S., Pardon, E., Lee, M.Y., Cherezov, V., Majumdar, S., Zaidi, S.A., Ondachi, P., Wacker, D., Huang, X.P., Strachan, R.T., Vardy, E., Che, T., Carroll, F.I., Uprety, R., Mosier, P.D., Tribo, A.R., Stevens, R.C.
copyrightData provided by Research Collaboration for Structural Biology, Han, G.W., Roth, B.L., Krumm, B.E., Katritch, V., Steyaert, J., Pasternak, G.W., McCorvy, J.D., Wang, S., Pardon, E., Lee, M.Y., Cherezov, V., Majumdar, S., Zaidi, S.A., Ondachi, P., Wacker, D., Huang, X.P., Strachan, R.T., Vardy, E., Che, T., Carroll, F.I., Uprety, R., Mosier, P.D., Tribo, A.R., Stevens, R.C. , provided free of copyright via the Protein DataBank. View original data or read license terms.
