PDB | 6b3j Biased agonist-bound human GLP-1 receptor-Gs complex

3.3 angstrom phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex

label Keywords
class b g protein-coupled receptor, agonist-receptor-g protein ternary complex, glucagon-like peptide 1 receptor, active-state g protein-coupled receptor, signaling protein, phase plate, phase contrast, single particle cryo-em
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands

Original publication

import_contacts Title
Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex.
import_contacts Journal
Nature 2018
import_contacts DOI
10.1038/nature25773
person Authors
Sexton, P.M., Radjainia, M., Koole, C., Khoshouei, M., Glukhova, A., Baumeister, W., Zhao, P., Wootten, D., Wang, M.W., Danev, R., Thal, D.M., Miller, L.J., Clydesdale, L., Liang, Y.L., Christopoulos, A., Furness, S.G.B., Lei, S., Truong, T.T.

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