PDB | 6awq Anomalous chloride signal reveals the position of sertraline complexed
Anomalous chloride signal reveals the position of sertraline complexed with the serotonin transporter at the central site
label Keywords
neurotransmitter transporter, antidepressant, transport protein
event_note Published
12/25/2024
blur_on Resolution
4.046 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, CHLORIDE ION, SODIUM ION
Original publication
import_contacts Title
Structural basis for recognition of diverse antidepressants by the human serotonin transporter.
import_contacts Journal
Nat. Struct. Mol. Biol. 2018
import_contacts DOI
10.1038/s41594-018-0026-8
person Authors
Gouaux, E., Coleman, J.A.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Gouaux, E., Coleman, J.A. , provided free of copyright via the Protein DataBank. View original data or read license terms.