PDB | 6awq Anomalous chloride signal reveals the position of sertraline complexed

Anomalous chloride signal reveals the position of sertraline complexed with the serotonin transporter at the central site

label Keywords
neurotransmitter transporter, antidepressant, transport protein
event_note Published
12/25/2024
blur_on Resolution
4.046 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, CHLORIDE ION, SODIUM ION

Original publication

import_contacts Title
Structural basis for recognition of diverse antidepressants by the human serotonin transporter.
import_contacts Journal
Nat. Struct. Mol. Biol. 2018
import_contacts DOI
10.1038/s41594-018-0026-8
person Authors
Gouaux, E., Coleman, J.A.

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