PDB | 6ajg Mycolic acid transporter MmpL3

Crystal structure of mycolic acid transporter MmpL3 from Mycobacterium smegmatis complexed with SQ109

label Keywords
membrane protein, transporter, rnd family, cell wall biosynthesis, drug target, hydrolase
event_note Published
08/27/2018
blur_on Resolution
2.604 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
N-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-N'-[(1R,3S,5R,7R)-tricyclo[3.3.1.1~3,7~]dec-2-yl]ethane-1,2-diamine, DODECYL-BETA-D-MALTOSIDE, (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID

Original publication

import_contacts Title
Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target.
import_contacts Journal
Cell 2019
import_contacts DOI
10.1016/j.cell.2019.01.003
person Authors
Rao, Z., Zhang, L., Cheng, X., Jiang, H., Yang, H., Guddat, L.W., Zhang, B., Jiang, B., Li, J., Zhao, Y., Zhang, J., Wu, L., Liu, Z., Yang, X., Yang, Y.

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