PDB | 5zkc Rationally thermostabilized M2 muscarinic acetylcholine receptor
Crystal structure of rationally thermostabilized M2 muscarinic acetylcholine receptor bound with NMS
label Keywords
gpcr crystallography, rationally thermostabilized mutant, membrane protein-inhibitor complex
event_note Published
10/23/2024
blur_on Resolution
2.3 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
N-methyl scopolamine
Original publication
import_contacts Title
Structural insights into the subtype-selective antagonist binding to the M2muscarinic receptor
import_contacts Journal
Nat. Chem. Biol. 2018
import_contacts DOI
10.1038/s41589-018-0152-y
person Authors
Kinoshita, M., Yasuda, S., Tsujimoto, H., Kobilka, B.K., Horita, S., Suno, R., Hirata, K., Kobayashi, T., Yamashita, K., Yamamoto, M., Vaidehi, N., Murata, T., Tawaramoto, M.S., Maeda, S., Iwata, S., Lee, S.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Kinoshita, M., Yasuda, S., Tsujimoto, H., Kobilka, B.K., Horita, S., Suno, R., Hirata, K., Kobayashi, T., Yamashita, K., Yamamoto, M., Vaidehi, N., Murata, T., Tawaramoto, M.S., Maeda, S., Iwata, S., Lee, S. , provided free of copyright via the Protein DataBank. View original data or read license terms.
