PDB | 5zcq Azide-bound cytochrome c oxidase structure determined using the crystals exposed to 10 mM azide solution for 2 days
Azide-bound cytochrome c oxidase structure determined using the crystals exposed to 10 mM azide solution for 2 days
label Keywords
metalloenzyme cytochrome c oxidase proton pump bioenergetics heme copper, membrane protein, oxidoreductase
event_note Published
02/19/2018
blur_on Resolution
1.65 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
HEME-A, COPPER (II) ION, MAGNESIUM ION, SODIUM ION, AZIDE ION, TRISTEAROYLGLYCEROL, (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 1,2-ETHANEDIOL, CHOLIC ACID, DINUCLEAR COPPER ION, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, DECYL-BETA-D-MALTOPYRANOSIDE, UNKNOWN ATOM OR ION, CARDIOLIPIN, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, ZINC ION
Original publication
import_contacts Title
X-ray structural analyses of azide-bound cytochromecoxidases reveal that the H-pathway is critically important for the proton-pumping activity.
import_contacts Journal
J. Biol. Chem. 2018
import_contacts DOI
10.1074/jbc.RA118.003123
person Authors
Hatano, K., Tsukihara, T., Yano, N., Shinzawa-Itoh, K., Muramoto, K., Yoshikawa, S., Tadehara, H., Shimada, A., Yamashita, E.
copyrightData provided by Research Collaboration for Structural Biology, Hatano, K., Tsukihara, T., Yano, N., Shinzawa-Itoh, K., Muramoto, K., Yoshikawa, S., Tadehara, H., Shimada, A., Yamashita, E. , provided free of copyright via the Protein DataBank. View original data or read license terms.
