PDB | 5zbq Human neuropeptide Y Y1 receptor

The Crystal Structure of human neuropeptide Y Y1 receptor with UR-MK299

label Keywords
g protein-coupled receptor, receptor inhibitor, complex structure, signaling protein
event_note Published
10/23/2024
blur_on Resolution
2.7 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
N~2~-(diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-N~5~-(N'-{[2-(propanoylamino)ethyl]carbamoyl}carbamimidoyl)-D-ornithinamide

Original publication

import_contacts Title
Structural basis of ligand binding modes at the neuropeptide Y Y1receptor
import_contacts Journal
Nature 2018
import_contacts DOI
10.1038/s41586-018-0046-x
person Authors
Zhao, Q., Buschauer, A., Ye, S., Larhammar, D., Bosse, M., Kaiser, A., Meiler, J., Beck-Sickinger, A.G., Wifling, D., Schmidt, P., Bernhardt, G., Yi, C., Yang, Z., Burkert, K., Wu, B., Kogler, L.M., Huster, D., Xu, B., Zhang, R., Bender, B.J., Keller, M., Li, B., Littmann, T., Han, S., Plank, N., Stevens, R.C.

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