PDB | 5zbh Human Neuropeptide Y Y1 Receptor

The Crystal Structure of Human Neuropeptide Y Y1 Receptor with BMS-193885

label Keywords
g protein-coupled receptor neuropeptide y y1 receptor inhibitor complex structure, signaling protein
event_note Published
10/16/2024
blur_on Resolution
3 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
dimethyl 4-{3-[({3-[4-(3-methoxyphenyl)piperidin-1-yl]propyl}carbamoyl)amino]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Original publication

import_contacts Title
Structural basis of ligand binding modes at the neuropeptide Y Y1receptor
import_contacts Journal
Nature 2018
import_contacts DOI
10.1038/s41586-018-0046-x
person Authors
Zhao, Q., Buschauer, A., Ye, S., Larhammar, D., Bosse, M., Kaiser, A., Meiler, J., Beck-Sickinger, A.G., Wifling, D., Schmidt, P., Bernhardt, G., Yi, C., Yang, Z., Burkert, K., Wu, B., Kogler, L.M., Huster, D., Xu, B., Zhang, R., Bender, B.J., Keller, M., Li, B., Littmann, T., Han, S., Plank, N., Stevens, R.C.

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