PDB | 5yw7 Structure of pancreatic ATP-sensitive potassium channel

Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on SUR1 ABC transporter module at 4.4A)

label Keywords
katp, channel, glibenclamide, sulfonylurea, membrane protein
event_note Published
03/27/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER

Original publication

import_contacts Title
Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
import_contacts Journal
Protein Cell 2018
import_contacts DOI
10.1007/s13238-018-0530-y
person Authors
Kang, Y., Ding, D., Zeng, X., Wu, J.X., Wang, M., Chen, L.

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