PDB | 5yve Human P2X3 receptor
Crystal structure of human P2X3 receptor in complex with the AF-219 negative allosteric modulator
label Keywords
ion channels, atp, transport protein
event_note Published
10/16/2024
blur_on Resolution
3.4 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
MAGNESIUM ION, SODIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[2,4-bis(azanyl)pyrimidin-5-yl]oxy-2-methoxy-4-propan-2-yl-benzenesulfonamide
Original publication
import_contacts Title
Druggable negative allosteric site of P2X3 receptors.
import_contacts Journal
Proc. Natl. Acad. Sci. U.S.A. 2018
import_contacts DOI
10.1073/pnas.1800907115
person Authors
Zhao, W.S., Wang, J., Cheng, X.Y., Hattori, M., Sun, W.S., Cao, P., Huang, Y., Liu, Y., Cui, W.W., Zhu, M.X., Wang, R., Wang, Y., Yang, Y., Yu, Y.
copyrightData provided by Research Collaboration for Structural Biology, Zhao, W.S., Wang, J., Cheng, X.Y., Hattori, M., Sun, W.S., Cao, P., Huang, Y., Liu, Y., Cui, W.W., Zhu, M.X., Wang, R., Wang, Y., Yang, Y., Yu, Y. , provided free of copyright via the Protein DataBank. View original data or read license terms.
