PDB | 5xr8 Crystal structure of the human CB1 in complex with agonist AM841
Crystal structure of the human CB1 in complex with agonist AM841
label Keywords
membrane protein, human g protein-coupled receptor, stabilizing agonists, lipidic cubic phase, signaling protein
event_note Published
06/07/2017
blur_on Resolution
2.95 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
FLAVIN MONONUCLEOTIDE, (6~{a}~{R},9~{R},10~{a}~{R})-9-(hydroxymethyl)-3-(8-isothiocyanato-2-methyl-octan-2-yl)-6,6-dimethyl-6~{a},7,8,9,10,10~{a}-hexahydrobenzo[c]chromen-1-ol, CHOLESTEROL, DI(HYDROXYETHYL)ETHER
Original publication
import_contacts Title
Crystal structures of agonist-bound human cannabinoid receptor CB1.
import_contacts Journal
Nature 2017
import_contacts DOI
10.1038/nature23272
person Authors
Zhao, S., Stevens, R.C., Liu, Z.J., Wu, Y., Hua, T., Pu, M., Vemuri, K., Han, G.W., Ding, K., Qu, L., Liu, H., Laprairie, R.B., Korde, A., Bohn, L.M., Ho, J.H., Nikas, S.P., Jiang, S., Li, X., Makriyannis, A., Hanson, M.A.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Zhao, S., Stevens, R.C., Liu, Z.J., Wu, Y., Hua, T., Pu, M., Vemuri, K., Han, G.W., Ding, K., Qu, L., Liu, H., Laprairie, R.B., Korde, A., Bohn, L.M., Ho, J.H., Nikas, S.P., Jiang, S., Li, X., Makriyannis, A., Hanson, M.A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
