PDB | 5wiv Structure of the sodium-bound human D4 Dopamine receptor
Structure of the sodium-bound human D4 Dopamine receptor in complex with Nemonapride
label Keywords
gpcr, dopamine receptor, antagonist, sodium, signaling protein-antagonist complex
event_note Published
10/30/2024
blur_on Resolution
2.143 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
Nemonapride, PHOSPHATE ION, OLEIC ACID, DI(HYDROXYETHYL)ETHER, SODIUM ION
Original publication
import_contacts Title
D4 dopamine receptor high-resolution structures enable the discovery of selective agonists.
import_contacts Journal
Science 2017
import_contacts DOI
10.1126/science.aan5468
person Authors
Shoichet, B.K., Che, T., Betz, R.M., Dror, R.O., Venkatakrishnan, A.J., Roth, B.L., McCorvy, J.D., Wang, S., Wacker, D., Huang, X.P., Levit, A.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Shoichet, B.K., Che, T., Betz, R.M., Dror, R.O., Venkatakrishnan, A.J., Roth, B.L., McCorvy, J.D., Wang, S., Wacker, D., Huang, X.P., Levit, A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
