PDB | 5unf Human angiotensin II type 2 receptor (Monoclinic form)
XFEL structure of human angiotensin II type 2 receptor (Monoclinic form) in complex with compound 1 (N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl])
label Keywords
human angiotensin ii receptor complex, gpcr signaling, gpcr, bril, membrane protein, lcp, xfel, blood pressure regulation, monoclinic crystal, compound 1 (cpd 1), signaling protein
event_note Published
11/06/2024
blur_on Resolution
2.8 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)thiophene-2-carboxamide
Original publication
import_contacts Title
Structural basis for selectivity and diversity in angiotensin II receptors.
import_contacts Journal
Nature 2017
import_contacts DOI
10.1038/nature22035
person Authors
Patel, N., Soisson, S.M., Han, G.W., Ishchenko, A., Tolstikova, A., Hollenstein, K., Babaoglu, K., Shipman, J.M., Katritch, V., Zhang, H., Garcia-Calvo, M., Katz, R.D., Batyuk, A., Liu, W., Sharma, S., Weierstall, U., Cherezov, V., Moore, E.L., Stevens, R.C., White, K.L., White, T.A., Hunter, M.S., Sheth, P., Sadybekov, A., Zamlynny, B., Rudd, M.T.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Patel, N., Soisson, S.M., Han, G.W., Ishchenko, A., Tolstikova, A., Hollenstein, K., Babaoglu, K., Shipman, J.M., Katritch, V., Zhang, H., Garcia-Calvo, M., Katz, R.D., Batyuk, A., Liu, W., Sharma, S., Weierstall, U., Cherezov, V., Moore, E.L., Stevens, R.C., White, K.L., White, T.A., Hunter, M.S., Sheth, P., Sadybekov, A., Zamlynny, B., Rudd, M.T. , provided free of copyright via the Protein DataBank. View original data or read license terms.
