PDB | 5ul0 S. Cerevisiae Cyp51 Complexed

S. CEREVISIAE CYP51 COMPLEXED WITH VT-1161

label Keywords
vt-1161, cyp51, oxidoreductase-oxidoreducatse inhibitor complex, sterol biosynthesis, oxidoreductase
event_note Published
01/23/2017
blur_on Resolution
2.2 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
PROTOPORPHYRIN IX CONTAINING FE, (R)-2-(2,4-Difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol, PENTAETHYLENE GLYCOL

Original publication

import_contacts Title
Azole Resistance Reduces Susceptibility to the Tetrazole Antifungal VT-1161.
import_contacts Journal
Antimicrob.Agents Chemother. 2019
import_contacts DOI
10.1128/AAC.02114-18
person Authors
Graham, D.O., Tyndall, J.D.A., Hassan, H.F., Wilson, R.K., Monk, B.C., Chen, D., Sabherwal, M., Keniya, M.V.

Loading