PDB | 5ul0 S. Cerevisiae Cyp51 Complexed
S. CEREVISIAE CYP51 COMPLEXED WITH VT-1161
label Keywords
vt-1161, cyp51, oxidoreductase-oxidoreducatse inhibitor complex, sterol biosynthesis, oxidoreductase
event_note Published
01/23/2017
blur_on Resolution
2.2 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
PROTOPORPHYRIN IX CONTAINING FE, (R)-2-(2,4-Difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol, PENTAETHYLENE GLYCOL
Original publication
import_contacts Title
Azole Resistance Reduces Susceptibility to the Tetrazole Antifungal VT-1161.
import_contacts Journal
Antimicrob.Agents Chemother. 2019
import_contacts DOI
10.1128/AAC.02114-18
person Authors
Graham, D.O., Tyndall, J.D.A., Hassan, H.F., Wilson, R.K., Monk, B.C., Chen, D., Sabherwal, M., Keniya, M.V.
copyrightData provided by Research Collaboration for Structural Biology, Graham, D.O., Tyndall, J.D.A., Hassan, H.F., Wilson, R.K., Monk, B.C., Chen, D., Sabherwal, M., Keniya, M.V. , provided free of copyright via the Protein DataBank. View original data or read license terms.