PDB | 5uen Human adenosine A1 receptor A1AR-bRIL
Crystal structure of the human adenosine A1 receptor A1AR-bRIL in complex with the covalent antagonist DU172 at 3.2A resolution
label Keywords
gpcr, transmembrane, receptor, adenosine, membrane protein
event_note Published
11/20/2024
blur_on Resolution
3.2 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
4-{[3-(8-cyclohexyl-2,6-dioxo-1-propyl-1,2,6,7-tetrahydro-3H-purin-3-yl)propyl]carbamoyl}benzene-1-sulfonyl fluoride, OLEIC ACID
Original publication
import_contacts Title
Structure of the Adenosine A1 Receptor Reveals the Basis for Subtype Selectivity.
import_contacts Journal
Cell 2017
import_contacts DOI
10.1016/j.cell.2017.01.042
person Authors
Sexton, P.M., Jorg, M., Nguyen, A.T., Vecchio, E.A., Glukhova, A., Scammells, P.J., May, L.T., Thal, D.M., Christopoulos, A.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Sexton, P.M., Jorg, M., Nguyen, A.T., Vecchio, E.A., Glukhova, A., Scammells, P.J., May, L.T., Thal, D.M., Christopoulos, A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
