PDB | 5tio Human Glycine Receptor alpha-3 Bound to AM-3607

Crystal Structure of Human Glycine Receptor alpha-3 Bound to AM-3607

label Keywords
ligand-gated ion channel neurotransmitter receptor membrane protein cys-loop receptor, transport protein
event_note Published
11/20/2024
blur_on Resolution
3.25 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(3S,3aS,9bS)-2-[(2H-1,3-benzodioxol-5-yl)sulfonyl]-3,5-dimethyl-1,2,3,3a,5,9b-hexahydro-4H-pyrrolo[3,4-c][1,6]naphthyridin-4-one, GLYCINE, ZINC ION, 2-acetamido-2-deoxy-beta-D-glucopyranose

Original publication

import_contacts Title
Crystal Structures of Human GlyRa3 Bound to a Novel Class of Potentiators with Efficacy in a Mouse Model of Neuropathic Pain
import_contacts Journal
To Be Published ?
import_contacts DOI
?
person Authors
Michelsen, K., Zhang, M., Ayube, S., McDonough, S.I., Huang, X., Bregman, H., Gingras, J., Lehto, S.G., Luther, J.A., Shaffer, P.L., Yi, S., Simard, J.R., Chen, H., Matson, D.J., Schneider, S., DiMauro, E.F., Plant, M.M., Teffera, Y.

Loading