PDB | 5tin Human Glycine Receptor alpha-3 Mutant N38Q Bound to AM-3607
Crystal Structure of Human Glycine Receptor alpha-3 Mutant N38Q Bound to AM-3607
label Keywords
ligand-gated ion channel neurotransmitter receptor membrane protein cys-loop receptor, transport protein
event_note Published
11/06/2024
blur_on Resolution
2.61 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(3S,3aS,9bS)-2-[(2H-1,3-benzodioxol-5-yl)sulfonyl]-3,5-dimethyl-1,2,3,3a,5,9b-hexahydro-4H-pyrrolo[3,4-c][1,6]naphthyridin-4-one, GLYCINE, ZINC ION, CHLORIDE ION
Original publication
import_contacts Title
Crystal Structures of Human GlyRa3 Bound to a Novel Class of Potentiators with Efficacy in a Mouse Model of Neuropathic Pain
import_contacts Journal
To Be Published ?
import_contacts DOI
?
person Authors
Michelsen, K., Zhang, M., Ayube, S., McDonough, S.I., Huang, X., Bregman, H., Gingras, J., Lehto, S.G., Luther, J.A., Shaffer, P.L., Yi, S., Simard, J.R., Chen, H., Matson, D.J., Schneider, S., DiMauro, E.F., Plant, M.M., Teffera, Y.
copyrightData provided by Research Collaboration for Structural Biology, Michelsen, K., Zhang, M., Ayube, S., McDonough, S.I., Huang, X., Bregman, H., Gingras, J., Lehto, S.G., Luther, J.A., Shaffer, P.L., Yi, S., Simard, J.R., Chen, H., Matson, D.J., Schneider, S., DiMauro, E.F., Plant, M.M., Teffera, Y. , provided free of copyright via the Protein DataBank. View original data or read license terms.
